What is Lacine Plus?

Lacine Plus (Losartan + Hydrochlorothiazide) is a combination medication used to manage hypertension (high blood pressure) in patients whose blood pressure is not adequately controlled by either Losartan or Hydrochlorothiazide alone. By combining an angiotensin II receptor blocker (ARB) and a thiazide diuretic, Lacine Plus helps to reduce blood pressure effectively and lower the risk of heart attack, stroke, and kidney complications.

Benefits

Lacine Plus provides multiple cardiovascular benefits through its dual mechanism of action. Key benefits include:

• Effective blood pressure reduction when monotherapy is insufficient.
• Reduces the risk of stroke, heart attack, and kidney damage in hypertensive patients.
• Helps improve heart and vascular health by promoting better circulation.
• Maintains balanced blood volume and reduces fluid retention.
• Provides better long-term control of hypertension with once-daily dosing.

According to the FDA and Mayo Clinic, this combination therapy has proven efficacy for patients who require dual action to achieve optimal blood pressure control.

Dosage & Usage

Lacine Plus is available in the following dosage strengths: 50/12.5 mg, 100/12.5 mg, and 100/25 mg of Losartan and Hydrochlorothiazide, respectively. The appropriate dose depends on the patient’s condition and medical response.

• Initial dose: 50/12.5 mg once daily.
• Maintenance dose: May be increased to 100/25 mg once daily as needed to achieve target blood pressure.

Lacine Plus should be taken at the same time each day, preferably in the morning to avoid nocturnal urination. It may be taken with or without food. Always follow your doctor’s prescribed dosage and do not discontinue the medication without medical advice.

Storage

Store Lacine Plus tablets at room temperature, between 20°C and 25°C (68°F–77°F). Protect from moisture and light, and keep the medication out of reach of children and pets. Do not store in bathrooms or near heat sources.

Product Information

• Generic Name: Losartan + Hydrochlorothiazide
• Category: Cardiovascular
• Available Doses: 50/12.5 mg, 100/12.5 mg, 100/25 mg
• Type: Prescription (Rx)
• Pharmacologic Class: Angiotensin II Receptor Blocker + Thiazide Diuretic

How It Works

Lacine Plus (Losartan + Hydrochlorothiazide) combines two antihypertensive agents that act through complementary mechanisms:

• Losartan blocks the effects of angiotensin II, a hormone that constricts blood vessels and increases blood pressure. This leads to vasodilation and reduced vascular resistance.
• Hydrochlorothiazide is a thiazide diuretic that promotes the excretion of sodium and water through urine, decreasing fluid volume and blood pressure.

Together, these agents offer superior blood pressure reduction compared to monotherapy while maintaining a balanced electrolyte profile.

Who Should Use Lacine Plus

Lacine Plus is recommended for adults who:

• Have essential hypertension not adequately controlled by a single drug.
• Require a fixed-dose combination for better compliance and consistent results.
• Have cardiovascular risk factors such as diabetes, kidney disease, or prior cardiac events.

It should not be used in patients with severe renal impairment, anuria, or hypersensitivity to sulfonamide-derived drugs.

Buying Lacine Plus Online

You can purchase Lacine Plus (Losartan + Hydrochlorothiazide) securely through our online pharmacy. Ensure that your purchase is from an FDA-registered source and that your prescription is up to date. Compare product strengths and prices before placing your order.

Safety & Possible Side Effects

Lacine Plus is generally well-tolerated, but like all medications, it may cause some side effects. Common side effects include:

• Dizziness or lightheadedness
• Fatigue
• Frequent urination
• Low potassium or sodium levels
• Muscle cramps

Rare but serious adverse effects include kidney dysfunction, dehydration, and allergic reactions. Avoid using potassium supplements or salt substitutes without consulting your healthcare provider. Pregnant women should not take Lacine Plus due to potential harm to the fetus. For more detailed information, visit the WebMD page for Losartan + Hydrochlorothiazide.

FAQs

Can I take Lacine Plus with food?

Yes, Lacine Plus can be taken with or without food. However, it is best taken in the morning to prevent frequent urination at night.

Does Lacine Plus cause potassium loss?

Hydrochlorothiazide may lower potassium levels, but Losartan helps counterbalance this effect. Routine blood tests are recommended to monitor electrolytes.

Can I take Lacine Plus if I have kidney disease?

Patients with mild kidney impairment may use Lacine Plus under medical supervision, but it is contraindicated in severe renal dysfunction.

References

• U.S. Food & Drug Administration (FDA)
• Mayo Clinic – Losartan & Hydrochlorothiazide Overview
• WebMD – Losartan + Hydrochlorothiazide Oral