Podecif (Cefpodoxime Proxetil) – Uses, Dosage, and Side Effects
What is Podecif (Cefpodoxime Proxetil)?
Podecif (Cefpodoxime Proxetil) is a third-generation cephalosporin antibiotic used to treat a wide variety of bacterial infections. It is effective against both gram-positive and gram-negative bacteria and is commonly prescribed for respiratory tract, urinary tract, ear, and skin infections. Podecif works by inhibiting bacterial cell wall synthesis, leading to the destruction of the bacteria. It is available in 100mg and 200mg tablet strengths for oral administration.
Benefits
Podecif (Cefpodoxime Proxetil) offers broad-spectrum antibacterial coverage with high bioavailability and reliable clinical outcomes. Key therapeutic benefits include:
- Treatment of acute otitis media and pharyngitis/tonsillitis.
- Effective against community-acquired pneumonia and acute bacterial bronchitis exacerbations.
- Used for acute uncomplicated gonorrhea (urethral, cervical, and ano-rectal infections in women).
- Helps manage skin and skin structure infections.
- Treats acute maxillary sinusitis and uncomplicated urinary tract infections (cystitis).
- Provides a convenient oral alternative to injectable cephalosporins for outpatient therapy.
Dosage & Usage
Podecif (Cefpodoxime Proxetil) is available in 100mg and 200mg tablets. The dosage depends on the type and severity of the infection:
- Pharyngitis/Tonsillitis: 100mg every 12 hours for 10 days.
- Acute Otitis Media: 100mg every 12 hours for 10 days (for children, as directed by a physician).
- Community-Acquired Pneumonia: 200mg every 12 hours for 14 days.
- Acute Bronchitis: 200mg every 12 hours for 10 days.
- Uncomplicated Gonorrhea: Single 200mg oral dose.
- Skin and Skin Structure Infections: 200mg every 12 hours for 7–14 days.
- Urinary Tract Infections (Cystitis): 100mg every 12 hours for 7 days.
Take Podecif with food to enhance absorption. Do not skip doses or discontinue use early, as incomplete therapy may lead to bacterial resistance. Always follow your healthcare provider’s exact prescription.
Storage
Store Podecif tablets below 30°C (86°F) in a cool, dry place away from moisture and direct sunlight. Keep out of reach of children. Do not use after the expiration date printed on the packaging.
Product Information
- Generic Name: Cefpodoxime Proxetil
- Brand Name: Podecif
- Category: Anti-infective / Cephalosporin Antibiotic
- Dosage Forms: 100mg and 200mg tablets
- Route of Administration: Oral
- Prescription Required: Yes
How It Works
Cefpodoxime Proxetil is a β-lactam antibiotic that interferes with bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This action inhibits the final transpeptidation step of peptidoglycan formation, weakening the bacterial cell wall and causing cell death. Its broad antimicrobial activity covers pathogens responsible for respiratory, urinary, and skin infections, such as Streptococcus pneumoniae, Haemophilus influenzae, Escherichia coli, and Neisseria gonorrhoeae.
Who Should Use Podecif (Cefpodoxime Proxetil)
Podecif is suitable for adults and children with bacterial infections sensitive to Cefpodoxime. It is prescribed for respiratory, ENT, skin, and urinary tract infections. Patients with a known allergy to cephalosporins or severe penicillin allergy should avoid this medication. Use with caution in patients with renal impairment, and consult a physician before taking if pregnant or breastfeeding.
Buying Podecif (Cefpodoxime Proxetil) Online
You can buy Podecif (Cefpodoxime Proxetil) 100mg and 200mg tablets from reputable online pharmacies or your local pharmacy. Ensure that you purchase only from verified and licensed sources. Visit our online pharmacy store for FDA-approved medications and professional support.
Safety & Possible Side Effects
Podecif (Cefpodoxime Proxetil) is generally safe and well tolerated. However, some patients may experience mild to moderate side effects, including:
- Nausea or vomiting
- Abdominal discomfort or diarrhea
- Headache or dizziness
- Rash or allergic skin reactions
- Temporary increase in liver enzymes
Serious adverse effects are rare but may include allergic reactions, anaphylaxis, or Clostridium difficile-associated diarrhea. Stop taking the medication and seek medical advice if severe reactions occur. Avoid using Podecif unnecessarily to prevent antibiotic resistance. For detailed safety guidance, visit the FDA Drug Database and WebMD Drug Information.
FAQs
Can Podecif be taken with food?
Yes, Podecif should be taken with food to improve absorption and reduce stomach upset.
Is Podecif safe for children?
Yes, Podecif is approved for pediatric use in appropriate doses as prescribed by a doctor.
Can I take Podecif if I’m allergic to penicillin?
Patients with mild penicillin allergies may tolerate Cefpodoxime, but cross-reactivity can occur. Consult your doctor before use.







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