What is Metrozole (Metronidazole)?

Metrozole (Metronidazole) is an antiprotozoal and antibacterial medication used to treat infections caused by anaerobic bacteria and certain parasites. It is highly effective against organisms such as Entamoeba histolytica, Trichomonas vaginalis, and Clostridium species. Metrozole is used to manage a variety of infections, including amebiasis, bacterial vaginosis, trichomoniasis, and intra-abdominal infections. It is available in 250mg, 500mg tablets, and 125mg/5ml suspension forms for oral use, as well as vaginal suppositories for localized infections.

Benefits

Metrozole (Metronidazole) provides effective treatment for bacterial and protozoal infections with both systemic and localized therapeutic benefits. Key advantages include:

• Treatment of extraintestinal and intestinal amebiasis, including amebic liver abscess.
• Effective against anaerobic bacterial infections such as brain abscesses, endocarditis, and intra-abdominal infections.
• Treats bacterial vaginosis and trichomoniasis in both men and women.
• Can be used in combination therapy for severe mixed bacterial infections.
• Available in multiple forms for both oral and vaginal administration.
• Rapid absorption and high efficacy with a wide therapeutic range.

Dosage & Usage

The dosage of Metrozole (Metronidazole) varies according to the type and severity of the infection and the patient’s age. It is available as 250mg and 500mg tablets, and a 125mg/5ml suspension for pediatric use.

• Amebiasis (Intestinal or Extraintestinal): Adults: 500–750mg every 8 hours for 7–10 days. Children: 35–50mg/kg/day divided into three doses.
• Bacterial Vaginosis (Oral): 500mg twice daily for 7 days.
• Bacterial Vaginosis (Vaginal Suppository): One suppository inserted once daily for 5–7 days.
• Trichomoniasis: 2g single dose or 500mg twice daily for 7 days (both partners should be treated simultaneously).
• Intra-Abdominal or CNS Infections: 500mg every 8 hours for 7–14 days (as part of combination therapy).

Take Metrozole with or after meals to reduce stomach upset. Do not consume alcohol during treatment and for at least 48 hours afterward, as it may cause severe nausea, vomiting, and headache due to disulfiram-like reactions.

Storage

Store Metrozole tablets and suspension at a temperature below 30°C (86°F), away from direct sunlight and moisture. Keep out of reach of children. The suspension should be shaken well before use and discarded after the expiration date indicated on the packaging.

Product Information

• Generic Name: Metronidazole
• Brand Name: Metrozole
• Category: Antiprotozoal / Antibacterial Drug
• Dosage Forms: Tablets (250mg, 500mg), Suspension (125mg/5ml), Vaginal Suppositories
• Route of Administration: Oral or Vaginal
• Prescription Required: Yes

How It Works

Metronidazole, the active component of Metrozole, acts by disrupting the DNA synthesis of anaerobic bacteria and protozoa. Once it enters the microbial cell, it undergoes reduction to form reactive nitro radicals, which bind to DNA and inhibit nucleic acid synthesis. This results in cell death and infection clearance. It is effective against a broad spectrum of anaerobic bacteria and protozoa, including Bacteroides fragilis, Clostridium species, Entamoeba histolytica, and Trichomonas vaginalis.

Who Should Use Metrozole (Metronidazole)

Metrozole is recommended for adults and children suffering from bacterial or protozoal infections caused by susceptible organisms. It is particularly indicated for patients with amebiasis, trichomoniasis, or bacterial vaginosis. However, it should be used under medical supervision, especially in pregnant women (particularly in the first trimester), nursing mothers, and patients with liver disease or blood disorders.

Buying Metrozole (Metronidazole) Online

You can purchase Metrozole (Metronidazole) tablets or suspension from verified online pharmacies or local medical stores. Always choose licensed and reputable sources to ensure product authenticity. Visit our online pharmacy store to buy FDA-approved medications safely and conveniently.

Safety & Possible Side Effects

Metrozole (Metronidazole) is generally safe and well tolerated when taken as prescribed. However, some individuals may experience mild to moderate side effects, such as:

• Nausea or vomiting
• Metallic taste in the mouth
• Abdominal cramps or diarrhea
• Headache or dizziness
• Dark-colored urine

Serious but rare side effects include allergic skin reactions, seizures, peripheral neuropathy, and liver toxicity. Stop the medication and seek medical help immediately if you experience rash, numbness, or difficulty breathing. Avoid alcohol during therapy and for 48 hours afterward.

For complete safety information, refer to trusted medical resources such as the FDA Drug Database and WebMD Drug Information.

FAQs

Can I take Metrozole with food?

Yes, it is advisable to take Metrozole with or after food to minimize gastrointestinal discomfort.

Can I drink alcohol while taking Metrozole?

No, alcohol should be avoided during treatment and for at least 48 hours after the last dose, as it may cause adverse reactions such as nausea, flushing, and rapid heartbeat.

Is Metrozole safe during pregnancy?

Metrozole should only be used during pregnancy if clearly needed and prescribed by a doctor, especially avoiding use during the first trimester.

References

• U.S. Food and Drug Administration (FDA)
• WebMD – Drug Information
• Mayo Clinic – Drugs & Supplements